To provide a safe haven to communicate and meet others without public interference. This works well for boards of directors. What about a dating app. You could argue it is too touristy or boring or it is not even the world s longest train ride or that there are many more exciting and authentic train journeys around the world and CIS, but it is a trip every traveller will want to do.
Drug therapy with bisphosphonates or denosumab to reduce bone disease and pain when cancer has spread to the bone.